EP 94: Alnylam’s Dr Paul Nioi on how genetics is used in drug target discovery

March 16th, 2023  |  44 mins 52 secs

alynlam, our future health, population genomics, sano genetics, target discovery, uk biobank

In this jam-packed 45-minute episode, we’re joined by Dr Paul Nioi, Vice President of Discovery and Translational Research at Alnylam Pharmaceuticals and Chair of the Founders Board for Our Future Health.

EP 93: International Perspectives on Access to Genetic Testing in ALS

January 24th, 2023  |  41 mins 20 secs

als, dr patrick short, genetics, international als, precision medicine, sano genetics

In this webinar, Paul Wicks leads the discussion with Professor Ammar Al-Chalabi, Dr Patrick Short and Kristina Salmon on international perspectives on genetic testing for ALS.

EP 92: Four Predictions for 2023

January 5th, 2023  |  13 mins 41 secs

genetics, genetics 2023, genetics predictions

From changing drug pricing legislation to AI breakthroughs, in the first episode of The Genetics Podcast for 2023, Patrick makes four predictions for the biggest stories of 2023.

EP 91: 2022 Genetics Round-up with Dr Veera Rajagopal

December 24th, 2022  |  1 hr 29 mins

dna 2022, genetics, genetics news, precision medicine, sano

In the final episode of The Genetics Podcast for 2022, we’re joined by Dr Veera Rajagopal, who is known as the ‘GWAS storyteller’ on Twitter for his prolific threads breaking down the latest findings in genetics.

EP 90: Patient-centric drug development in ALS with Ronald van der Geest, Chief Development Officer of Treeway

December 8th, 2022  |  35 mins 17 secs

als, ronald va der geest, treeway

This week Patrick is joined by Treeway Chief Development Officer Ronald van der Geest. Join them as they discuss Treeway's roots, the four major disciplines required for successful development of novel treatments, and the landscape of ALS.

EP 89: Baroness Nicola Blackwood on the UK's leading role in delivering 'genomic healthcare for everyone'

November 24th, 2022  |  33 mins 22 secs

baroness blackwood, genetic testing, genetics, genomics england, nicola blackwood

This week Patrick is joined by Baroness Nicola Blackwood of North Oxford. Nicola is chair of Genomics England, a diverse community of genomic clinicians and researchers providing a world-class service platform for genetic testing to patients.

EP 88: Precision oncology: how Next Generation Sequencing (NGS) is powering care today and the treatments of the future with Christine Ward (Takeda) and Geoff Oxnard (Foundation Medicine)

November 10th, 2022  |  42 mins 30 secs

clinicalgenetics, genetics, precisionmedicine, thegeneticspodcast

In this episode, guests Christine Ward, VP and Head of Oncology and Cell Therapy Precision & Translational Medicine at Takeda and Geoff Oxnard, Thoracic Oncologist and VP of Foundation Medicine talk to Patrick about Next Generation Sequencing (NGS) in precision oncology.

EP 87: Representation Matters: Why equitable access and community engagement are critical in genetic research

October 27th, 2022  |  49 mins 46 secs

diversity, precisionmedicine, representation, sanogenetics

In the age of precision medicine, ensuring equitable access and representation from participants of all communities is of vital importance when conducting genetic research.

EP 86: Heidi Rehm PhD, Chief Genomics Officer at Massachusetts General Hospital on curating and collaborating genomic datasets to guide the future of diagnostic and clinical research

October 13th, 2022  |  36 mins 59 secs

clinicalgenetics, genetics, precisionmedicine, thegeneticspodcast

Patrick speaks to Heidi Rehm who is at the top of the field of genome interpretation and medical genetics.

EP 85: Dr Jessica Kissinger on large-scale parasite genomics and the power of multi-omic data

September 29th, 2022  |  33 mins 55 secs

biology, genetics, pathogens, thegeneticspodcast

In this episode, we explore major findings in the field and Dr Kissinger's vision of large-scale interoperable datasets driving novel discoveries. Plus, Dr Kissinger shares her recent and personal experience of diagnosis with a rare disease, Ehlers-Danlos Syndrome, that puts everything into perspective.

EP 84: Mark Kotter, CEO, and Founder of bit.bio, on creating every cell type and kickstarting a cell therapy revolution

September 1st, 2022  |  34 mins 50 secs

bitbio, drugdiscovery, genetics, thegeneticspodcast

Doctors have been transplanting organs for decades, but can we transplant reprogrammed stem cells to rejuvenate the human body?

EP 83: Daphne Koller, Founder & CEO of Insitro - Integrating machine learning and biology at scale to reimagine drug discovery

August 11th, 2022  |  45 mins 10 secs

drugdiscovery, genetics, insitro, thegeneticspodcast

This week’s guest, Daphne Koller, is the Founder and CEO of Insitro - a company shifting the paradigm of new drug discovery using predictive models.

EP 82: Lessons from the world's largest genomic datasets with Daniel MacArthur, Director of the Centre for Population Genomics.

July 13th, 2022  |  45 mins 39 secs

This week’s guest, Daniel MacArthur, is the Director of the Centre for Population Genomics at the Garvan Institute of Medical Research and Murdoch Children's Research Institute.

EP 81: Cracking the druggable genome with Dietrich Stephan, Founder and CEO of NeuBase Therapeutics

June 29th, 2022  |  42 mins 38 secs

This week Patrick is joined by Dietrich Stephan, Founder and CEO of NeuBase Therapeutics.

EP 80: Rare disease genomics and the 'near-coding' genome with Nicky Whiffin, Group Leader at the Wellcome Centre for Human Genetics

June 15th, 2022  |  24 mins 39 secs

From decoding the genetics of rare disease using computational methods, to understanding the non-coding and 'near-coding' genome, this week Patrick is joined by Nicky Whiffin, Group Leader at the Wellcome Centre for Human Genetics and Sir Henry Dale Fellow at the University of Oxford.

EP 79: The Unknown Causes of Kidney Disease Project with Michael Spigler, Vice President of Patient Support and Education at American Kidney Fund

June 1st, 2022  |  30 mins 24 secs

In this week’s episode Patrick is joined by Michael Spigler, Vice President of Patient Support and Education at American Kidney Fund.