EP73: Ochre Bio: Building an in-silico liver model and addressing the impact and challenges of developing new treatments
November 24th, 2021 | 37 mins 11 secs
In this week’s episode Patrick speaks to Quin Wills and Jack O’ Meara, Co-Founders of Ochre Bio, about their founding story, why in-silico discoveries could be the road to faster and lower cost liver therapeutics, and the need for prioritising preventative measures against disease as the average human lifetime gets longer.
EP72: The DecodeME team on the challenges facing myalgic encephalomyelitis and chronic fatigue syndrome patients and the future of personalised treatments
November 10th, 2021 | 32 mins 25 secs
In this week’s episode Patrick speaks to Sonya Chowdhury, Chris Ponting and Andy Devereux-Cooke from the DecodeME project, the world’s largest genetic myalgic encephalomyelitis (ME) and chronic fatigue syndrome study
EP 71: Chief Medical Officer at LyGenesis, Professor Paulo Fontes, on the future of organ transplants
October 29th, 2021 | 36 mins 34 secs
This week’s guest, Paulo Fontes, is a Professor of Surgery and Chief Medical Officer at LyGenesis, an organ regeneration technology platform with a current focus on liver regeneration for patients with end stage liver disease.
EP70: The University of Oxford's Professor Cecilia Lindgren: understanding complex disease through big data and team science
October 14th, 2021 | 40 mins 5 secs
In this week’s episode Patrick speaks to Director of the Big Data Institute at University of Oxford, Professor Cecilia Lindgren, about her biggest eureka moment, the power of collaboration and consortiums across academia and industry to grow genetic sample sizes and accelerate research, and the importance of best practice standards to enable genetic research to scale successfully.
EP69: Chief Scientific Officer at Parkinson's Foundation, Dr James Beck, and Dr Ignacio Mata, Professor at the Cleveland Clinic, on the genetics of Parkinson’s disease and the future of precision treatments
September 24th, 2021 | 40 mins 41 secs
What is the role of genetics in Parkinson’s disease?
EP68: Dr Patrick Short features on GIANT’s Healthy Innovators Podcast and discusses the path to creating a successful startup in genomic medicine
September 1st, 2021 | 36 mins 53 secs
In this special episode we’re sharing Patrick’s guest appearance on GIANT’s Healthy Innovators Podcast.
EP67: Dr Anna Lewis from the Edmond J. Safra Center for Ethics at Harvard, on the biggest ethical questions in DNA sequencing and editing
August 18th, 2021 | 36 mins 17 secs
As more and more people get their DNA sequenced, through health care initiatives, biobanks and direct-to-consumer testing, an array of ethical questions arise.
EP 66: Professor David Strain, Senior Clinical Lecturer at the University of Exeter Medical School, on the emergence of Long COVID, its impact and how research is vital for supporting patients
August 4th, 2021 | 46 mins
For many Long COVID patients the debilitating long-term symptoms they experience emerged after what, at first, appeared to be a mild COVID-19 infection
EP 65: Dr Patrick Short guest features on The G Word podcast and discusses the power of translational research with CEO of Genomics England, Chris Wigley
June 30th, 2021 | 42 mins 19 secs
In this special episode we’re sharing Patrick’s guest appearance on Genomics England’s new podcast, The G Word.
Precision Pioneers EP 8: Chief Medical Officer at ESCAPE Bio, Dr Carrolee Barlow, on developing precision medicines for genetic forms of Parkinson’s disease
June 23rd, 2021 | 33 mins 36 secs
How can precision medicine techniques be used to develop potential new treatments for genetic Parkinson’s disease?
Precision Pioneers EP 7: Dr Vineeta Agarwala on investing in the future of precision medicine at the a16z bio fund
June 7th, 2021 | 46 mins 7 secs
Can the speed and success of COVID-19 trials teach us how to run other trials 5x faster going forward?
Precision Pioneers EP 6: Chief Medical Officer at ASC Therapeutics, Oscar Segurado, on the break-through application of CRISPR gene editing to treat haemophilia
May 19th, 2021 | 48 mins 22 secs
What have gene editing and gene therapies got to do with rockets and satellites?
Precision Pioneers EP 5: Alnylam's Josh Friedman on developing precision medicines for the 'silent killer' NASH/NAFLD
May 5th, 2021 | 34 mins 28 secs
On this episode of the podcast, Patrick is joined by Josh Friedman, Senior Director of Research at Alnylam Pharmaceuticals.
Precision Pioneers EP 4: Geneticist and Harvard professor, Robert Green on accelerating implementation of genomic medicine
April 21st, 2021 | 49 mins 21 secs
On this episode of the podcast Patrick is joined by Robert Green, a geneticist, Professor of Medicine at Harvard, and Director of the Preventive Genomics Clinic at Brigham Health, whose work centers around accelerating evidence based implementation of genomic medicine.
Precision Pioneers EP 3: CEO of Faze Medicines, Phil Vickers on 'Running toward challenges' in precision medicine development
April 7th, 2021 | 57 mins 6 secs
Continuing with our mini series of Precision Pioneers, Patrick is joined by Phil Vickers, President and CEO at Faze Medicines. Phil discusses his career, including his time with companies such as Merck and Shire Pharmaceuticals.
Precision Pioneers EP 2 - Aristea Therapeutics CMO Nihar Bhakta on developing precision medicines for both common and rare diseases
March 25th, 2021 | 55 mins 31 secs
This week Patrick talks to Nihar Bhakta as part of our series of ‘Precision Pioneers’. Dr Bhakta specialises in precision medicine and in this episode they focus on his work developing precision medicines for both common and rare diseases.